Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 13 4 2018 08 19 254 263 EN Masih Shafiei ​Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.and Department of Linguistics, University of Tübingen, Germany. Meng-Chuan Lai Child and Youth Mental Health Collaborative at the Centre for Addiction and Mental Health and The Hospital for Sick Children, and Department of Psychiatry, University of Toronto, Toronto, Canada. Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.Autism Research Centre,and Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.Department of Psychiatry, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan Amir-Hossein Memari Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. Fatemeh-Sadat Mirfazeli School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Sahar Zarei Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran Pouria Moshayedi Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, USA. Ramin Kordi Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran 2017 05 05 Objective: We aimed to examine the validity and reliability of the empathy quotient (EQ) and systemizing quotient (SQ) in a Farsi-speaking population. Method: This study explores the factor structure and psychometric properties of the Farsi translations of the 22-item version of EQ and the 25-item version of SQ among 542 young university students. Results: Applying a cross-validation approach, a 14-item two-factor model and a 15-item four-factor model for the Farsi translations of the short versions of EQ and SQ, respectively, were extracted from the exploratory dataset using exploratory factor analysis (EFA). Confirmatory factor analysis (CFA) on the validation dataset confirmed the factor structures identified by EFA. In addition, acceptable internal consistency and test-retest reliability were demonstrated for the Farsi translations of the 14-item two-factor EQ model and the 15-item four-factor SQ model. Conclusion: The results suggested further evidence in favor of the multi-factorial constructs of the EQ and SQ and validity and reliability of the scales. https://ijps.tums.ac.ir/index.php/ijps/article/view/1059 https://ijps.tums.ac.ir/index.php/ijps/article/download/1059/747