Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 16 1 2021 01 30 1 12 Seyyed Salman Alavi Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Mohammad Reza Mohammadi Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Zahra Hooshyari Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Soroush Mohammadi Kalhori Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Mona Salehi Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Maryam Salmanian Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Ali Khaleghi Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Hadi Zarafshan Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Ameneh Ahmadi Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran. Koorosh Kamali Social Determinants of Health Research Center, Zanjan University of Medical Sciences, Zanjan, Iran. Nastran Ahmadi Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. 2020 02 17 Objective: Psychosis is still among the most debilitating and severe mental disorders. The main objective of the present study was to investigate the estimated prevalence of psychotic disorders and finding the main predictors of psychotic disorders among Iranian children and adolescents. Method: Our total sample consisted of 30 553 individuals (49% males and 51%females) from 30 provinces of Iran, aged between 6 and 18 years, who were selected via cluster sampling method from urban and rural areas of all provinces. The data were analyzed using descriptive statistical analysis and multiple logistic regression method. Results: The results of multiple regression analysis showed that prevalence estimate of psychotic disorders was 0.25%. It was 0.3% and 0.2% in males and females, respectively. The age of 10-14 (OR = 2.24; 95% CI, 1.11-4.55) and the age of 15-18 (OR = 3.42; 95% CI, 1.74-6.75) were significant positive predictors, whereas none of the demographic variables were predictors for psychotic symptoms. Conclusion: This research highlights the main predictors of psychosis in children and adolescents. The study design also allowed a better understanding of predictors of psychotic disorders. The assessment of the prevalence of psychiatric disorders, particularly their comorbidities, may help to prevent mental illnesses in children and adolescents. https://ijps.tums.ac.ir/index.php/ijps/article/view/2009 https://ijps.tums.ac.ir/index.php/ijps/article/download/2009/980