Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 6 3 2011 09 15 125 127 Baktash Bayani Mashhad University of Medical Sciences, Heart research center Shakila Yousefi Islamic Azad university Torbat - e-Jam Branch, Khorasan Razavi, Iran Mahtab Bayani Zahedan University of Medical Sciences Maryam Shirmohammadi Psychiatry and Psychology research center, Tehran University of Medical Sciences Abdollatif Alimoradi Islamic Azad university Torbat - e-Jam Branch, Khorasan Razavi, Iran Homa Falsoleiman Mashhad University of Medical Sciences, Heart research center Narges Yazdi Psychiatry and Psychology research center, Tehran University of Medical Sciences Mohammad Arbabi Psychiatry and Psychology research center, Tehran University of Medical Sciences 2015 10 14 Objective: Cardiac diseases are psycho-somatic disorders, and psychological aspects play an essential role in their initiation and exacerbation. The aim of this study was to gain appropriate knowledge in the epidemiology of co-morbid depression and anxiety disorder in cardiovascular outpatients. Method: This study is descriptive with a sample of patients attending a cardio-vascular clinic. 238 individuals were included in this study using a consecutive sampling method. The study instrument was Hospital Anxiety and Depression Scale (HADS) questionnaire, which is a clinical scale for assessing anxiety and depression. Results: Of the 238 participants in this study, 93(38.7%) were male and 146 (61.3%) female. 28.5% of patients suffered from anxiety disorders , and 41.9% had depression. Regarding comorbid diseases such as diabetes mellitus, hyperlipidemia and hypertension, the severity of depression was just related to hypertension. There was a meaningful relationship between gender and symptoms of anxiety so that symptoms were more severe in women. Conclusion: Considering the high prevalence of depression and anxiety in patients suffering from cardio-vascular diseases, it is necessary to screen psychological disorders in patients with cardio-vascular diseases and improve their cardio-vascular health and quality of life as mush as possible. https://ijps.tums.ac.ir/index.php/ijps/article/view/253 https://ijps.tums.ac.ir/index.php/ijps/article/download/253/249