Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 5 3 2010 09 15 117 118 Vandad Sharifi Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Shahideh Amini Department of clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Padideh Ghaeli Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, IranDepartment of clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Arezoo Saeedinia Psychiatry and Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran 2015 10 14 Liver injury occurs with many drugs; therefore, a thorough work up is important for establishing the diagnosis. We report a case of trifluoperazine-induced cholestatic jaundice. A 44-year old male with schizoaffective disorder developed an increase in liver enzymes and jaundice after starting treatment with trifluoperazine. Workup for other potential etiologies was negative. https://ijps.tums.ac.ir/index.php/ijps/article/view/358 https://ijps.tums.ac.ir/index.php/ijps/article/download/358/354