Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 19 3 2024 06 11 315 326 Roya Vaziri Harami Behavioral Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Seyed Mehdi Samimi Ardestani Department of Psychiatry, Behavioral Sciences Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Seyed Saeed Sadr Department of Psychiatry, Behavioral Sciences Research Center, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Shaghayegh Dehghani MD, Department of psychiatry, school of medicine, Shahid Beheshti university of medical sciences, Tehran, Iran 2023 11 06 2024 06 10 Objectives: This study aimed to assess the validity and reliability of the complete Persian version of the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Autoquestionnaire (TEMPS-A) in an Iranian population. Materials and Methods: In this descriptive study, the TEMPS-A was first translated to Persian by a bilingual expert and was then back-translated to English by another expert and compared with the original version. The face validity and content validity of the Persian version of the questionnaire were confirmed following assessment by several psychiatrists. The Persian version of the questionnaire was then administered among 30 personnel of Imam Hossein Hospital to be completed. The same questionnaire was administered again among the same personnel after a 2-week interval to assess its reliability.  Results: The Cronbach’s alpha was calculated to be 0.911, indicating excellent reliability of the Persian version of the TEMPS-A. None of the questions required correction or omission. Some questions did not have a good correlation with the general scale but the correlation of the majority of them with the general scale was good. A significant difference was found in the mean scores of the questions (P<0.001), and the mean total score was 1.73. Conclusion: The present results showed excellent reliability of the complete Persian version of the TEMPS-A (> 0.9). Future studies are required to scrutinize the subscales of this questionnaire. https://ijps.tums.ac.ir/index.php/ijps/article/view/3730