Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 1 2 2006 06 15 59 64 Hamid Reza Pouretemad Department of Psychology, Shahid Beheshti University, Tehran, Iran Hamid Reza Naghavi Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Hossein Malekafzali Department of Biostatistics and Epidemiology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran Ahmad Ali Noorbala Department of Psychiatry, Hafez Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Harutiun Davidian Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Ahmad Ghanizadeh Department of Psychiatry, Hafez Hospital, Shiraz University of Medical Sciences, Shiraz, Iran Mohammad-Reza Mohammadi Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran National Research Center for Medical Sciences of Iran S. Abbas Bagheri Yazdi Mental Health Office, Ministry of Health and Medical Education, Tehran, Iran Mehdi Rahgozar Department of statistics and Computer, Social Welfare and Rehabilitation University, Tehran, Iran Javad Alaghebandrad Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Homayoun Amini Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Emran Mohammad Razzaghi Iranian National Center for Addiction Studies, Tehran University of Medical Sciences, Tehran, Iran Bita Mesgarpour National Research Center for Medical Sciences of Iran S. Nasir Ghaemi Department of Psychiatry and Behavioral Sciences, Rollins school of Public Health, Emory University School of Medicine, Atlanta, USA 2015 10 17 Objective: To study the prevalence and demographic characteristics of mood disorders among Iranian adults. Method: In this cross-sectional population-based epidemiological study (age > 18) in Iran, 25180 individuals were selected through a randomized cluster sampling method for a diagnosis using the Schedule for Affective Disorders and Schizophrenia (SADS). They were then interviewed at home by 250 trained clinical psychologists. Results: The estimated lifetime prevalence of Major Depressive Disorder (MDD) and Minor Depressive Disorder (mDD) were 3.1% and 0.3% respectively. Also, the estimated lifetime prevalence of Bipolar Mood disorder (BMD) type I and type II were 0.1% and 0.7% respectively. The current prevalence of MDD, mDD, BMD-I, and BMD-II were 1.8%, 0.2%, 0.04%, and 0.3% respectively. Mood disorders were associated with female gender, lower education, being married, being middle-aged, living in cities, and not being a homemaker. Conclusion: The prevalence of mood disorders was lower among Iranian adults than reported in Western studies, and a number of demographic associations differed from those reported in Western studies. Important cultural differences in the nature or manifestation of depression are implied by these results. https://ijps.tums.ac.ir/index.php/ijps/article/view/406 https://ijps.tums.ac.ir/index.php/ijps/article/download/406/401