Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 2 1 2007 03 15 35 40 Rozita Davari Department of Psychiatry, Shahid Beheshti University of Medical Sciences, Tehran, Iran Elham Shirazi Department of Psychiatry, Iran University of Medical Sciences, Mental Health Research Center, Tehran, Iran Zahra Shahrivar Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Amir Shabani Department of Psychiatry, Iran University of Medical Sciences, Mental Health Research Center, Tehran, Iran Vandad Sharifi Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran Javad Alagheband rad Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Mitra Hakimshooshtary Department of Psychiatry, Iran University of Medical Sciences, Mental Health Research Center, Tehran, Iran Mehdi Tehranidoost Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Homayoun Amini Department of Psychiatry, Tehran University of Medical Sciences, Tehran, Iran Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran 2015 10 17 Objectives: Culture may place a differential emphasis on particular emotions. The aim of this study is to find the most frequent symptoms in patients with major depressive disorder in Tehran. Method: 509 patients were recruited from 5 treatment settings. The sample was used from the project of assessing psychometric properties of CIDI in the Iranian population. The patients were evaluated by conducting clinical interviews and using DSM-IV criteria (American Psychiatric Association, 1994) for major depressive disorder. Results: Depressed mood (98.7%), sleep change (92.1%) and, fatigue / energy loss (89.4%) were the three highest-ranking symptoms. As cognitive factors, guiltiness and worthlessness were among the lowest ranking symptoms. There were no significant differences between men and women in frequency of symptoms with the exception of suicidal thoughts. Men had significantly higher suicidal thoughts than women. (P: 0. 01) Conclusion: Data were presented on the depressive symptomatology in population of Tehran. Key findings included a high rate of somatic symptoms in patients who suffered from MDD in this population. https://ijps.tums.ac.ir/index.php/ijps/article/view/433 https://ijps.tums.ac.ir/index.php/ijps/article/download/433/429