Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 4 1 2009 03 15 31 35 Najmeh Khosrovan Mehr Alzahra University, Psychology Faculty, Tehran, Iran. Child and Adolescent Psychiatry and Rehabilitation Center, Tehran, Iran Shahin Akhondzadeh Psychiatry and Psychology Research Center, Department of Psychiatry, Child and Adolescent Psychiatry Unit, Tehran University of Medical Sciences, Tehran, Iran Mohammad Reza Mohammadi Psychiatry and Psychology Research Center, Department of Psychiatry, Child and Adolescent Psychiatry Unit, Tehran University of Medical Sciences, Tehran, Iran Alzahra University, Psychology Faculty, Tehran, Iran Mohammad Mohammadi Psychiatry and Psychology Research Center, Department of Psychiatry, Child and Adolescent Psychiatry Unit, Tehran University of Medical Sciences, Tehran, IranChild and Adolescent Psychiatry and Rehabilitation Center, Tehran, Iran Somayeh Mahintorabi Child and Adolescent Psychiatry and Rehabilitation Center, Tehran, Iran 2015 10 17 Objectives: The aim of this randomized clinical trial was to assess the efficacy of stimdate compared to ritalin in the treatment of children with attention deficit hyperactivity disorder (ADHD). Method: Sixty four subjects (45 boys and 15 girls) aged 5-13 who were diagnosed with ADHD based on (DSM-IV-TR) criteria were selected for this study. The subjects were randomly assigned to two groups: one group with 30 subjects received stimdate and the other group of 30 subjects received ritalin for 6 weeks. Treatment outcomes were assessed using the Attention Deficit Hyperactivity Rating Scale administered at baseline and on weeks 2, 4 and 6 following the treatment. A two-way repeated measures analysis of variance (time- treatment interaction) was used. Results: There were no significant differences between sex, age, weight, and ethnicity of the participants in the 2 groups. Both groups showed a significant improvement during the 6 weeks of the treatment period, and this improvement was due to the parents' ADHD Rating Scale during the treatment. Conclusion: Based on the results of this study, no significant difference was observed between the two medications, and it seems both drugs behave[M1] in a similar way. In addition, stimdate appears to be effective and well tolerated for ADHD in children and adolescents in Iran. https://ijps.tums.ac.ir/index.php/ijps/article/view/495 https://ijps.tums.ac.ir/index.php/ijps/article/download/495/473