Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 44 51 Abbas Masoudzadeh Department of Psychiatry, Psychiatry and Behavioral Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Somayeh Alami Psychiatry and Behavioral Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Yazdan Naderi Rajeh Psychiatry and Behavioral Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran. Ehsan Taheri Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. Hajar Sadeghi Department of Nursing, Student Research Committee, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran. 2020 03 05 Objective: Domestic violence is an important social problem and according to the DSM5 classification, this problem is considered from a clinical point of view. Factors that play a role in the occurrence of domestic violence may include the personality traits of couples and the ways in which couples manage each other's emotions. The purpose of the study was to investigate the role of personality dimension and relationship emotional schema in prediction of domestic violence. Method: In this cross-sectional study, the study population included all men and women who referred to Sari forensic medicine in 2019 who were selected by convenience sampling. Data collection tools were Domestic Violence Scale, NEO Personality Questionnaire (NEO - FFI) and Relationship Emotional Schema (RESS). Data analysis was performed through correlation coefficients and regression analysis using SPSS 24 software. Results: Based on the results of stepwise regression analysis, negative relationship emotional schemas (Guilt/shame, Control, Numbness, Rational, Duration, Rumination, and Blame) and positive relationship emotional schemas (Comprehensibility, Validation, Differentiation, Values, Consensus, Acceptance, Expression) are the best predictor variable (R = 0.65; adjusted R square = 0.41; F = 44.41; P = 0.001), and personality dimension was excluded from the model because it did not have a significant predictive power. And was not able to explain the variance of domestic violence. Conclusion: According to the findings, the emotional schema of the relationship (negative/positive) and neuroticism play a key role in domestic violence. Therefore, by identifying the emotional schemas and personality traits of the couple's relationship, it is possible to provide more appropriate treatment outcomes for mental health professionals and effectively prevent the increase in domestic violence. https://ijps.tums.ac.ir/index.php/ijps/article/view/2064 https://ijps.tums.ac.ir/index.php/ijps/article/download/2064/1034

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 99 109 Arezoo Karimi Clinical Research Development Unit, Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran. Jafar Bazyar Pre-hospital Medical Emergency Organization, Ilam University of Medical Sciences, Ilam, Iran AND Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran. Leila Malekyan Department of Nursing, School of Nursing and Midwifery, Bam University of Medical Sciences, Bam, Iran. Salman Daliri Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran. 2020 12 16 Objective: After accidents and disasters, people suffer from mental disorders due to physical, economic and social injuries. These include anxiety, stress, depression, suicidal ideation, and suicide attempts. Due to the fact that some of these measures can endanger a person’s life, as a result, it is important to pay attention to these psychological factors. Accordingly, the present study was conducted to investigate the prevalence of suicidal ideation and suicide attempt after disaster in the world. Methods: The present study was a systematic review and meta-analysis of the prevalence of suicidal ideation and suicide attempt after disaster in the world. Accordingly, all English-language articles published from the beginning of 2000 to the end of 2019 were extracted through searches in the databases of Scopus, Web of Science, PubMed, Cochrane Library, Science Direct and Google scholar and then evaluated. Statistical analysis of data was performed using fixed and random effects model in meta-analysis, Cochran test and meta-regression. Results: A total of 33 studies with a sample size of 61,180 people entered the meta-analysis process. Accordingly, the prevalence of suicidal ideation was estimated at 12.9% (CI95%: 10.3% -15.5%) in the whole population, 5.2% (CI95%: 2.9% - 7.4%) in male and 15.8% (CI95%: 10.0% - 21.6%) in female. Moreover, the prevalence of suicide attempt after disasters was estimated at 8.8% (CI95%: 6.6% - 11.0%). Conclusion: Based on the findings of the present study, the prevalence of ​​ suicidal ideation and suicide attempt after disaster is high. Due to the fact that many people in the world are exposed to disasters every year, relatively many people deal with suicidal ideation or suicide attempts. https://ijps.tums.ac.ir/index.php/ijps/article/view/2498 https://ijps.tums.ac.ir/index.php/ijps/article/download/2498/1041

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 24 34 Samaneh Akbarpour Sleep Breathing Disorders Research Center (SBDRC), Tehran University of Medical Sciences, Tehran, Iran AND Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran. Amin Nakhostin-Ansari Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran. Khosro Sadeghniiat Haghighi Sleep Breathing Disorders Research Center (SBDRC), Tehran University of Medical Sciences, Tehran, Iran AND Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran Farnaz Etesam Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran AND Department of Psychiatry, Psychosomatic Medicine Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. Zahra Banafsheh Alemohammad Sleep Breathing Disorders Research Center (SBDRC), Tehran University of Medical Sciences, Tehran, Iran AND Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran. Faezeh Aghajani School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. Arezu Najafi Sleep Breathing Disorders Research Center (SBDRC), Tehran University of Medical Sciences, Tehran, Iran AND Occupational Sleep Research Center, Baharloo Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2020 07 25 Objective: COVID-19 pandemic has influenced almost every country worldwide. Being in a pandemic situation can cause psychological distress to people, which can lead to sleep disorders. The present study aimed to assess prevalence of depression, anxiety, and insomnia among Iranian people and their relations with COVID-19 fear in the early stages of COVID-19 pandemic. Method: A cross-sectional and population-based online study was designed. We created an online form and used Fear of COVID-19 scale (FCV-19), Generalized Anxiety Disorder 2 scale (GAD-2), Patient Health Questionnaire-2 (PHQ-2), and Insomnia Severity Index (ISI), to assess fear of COVID-19, anxiety, depression, and insomnia, respectively. We sent the link to the online survey to Iranians interested in participating in the study via social media, and 1223 Iranian completed the form. Results: A total of 1223 individuals with a mean age of 39.82 ± 10.75 years participated in the study. Prevalence of insomnia, depression and anxiety among our participants were 55.2%, 61.5%, and 50.9%, respectively. The mean FCV-19 score among the participants was 19.70 ± 5.08. Insomnia was more common among those who were 50 years or older. Fear of COVID-19 was related to a more risk of progression toward depression, anxiety, and insomnia. Conclusion: Fear of COVID-19 has a considerable association with depression, anxiety, and insomnia in the pandemic, and strategies to reasonably decrease people’s fears can help to reduce incidence of psychological issues during the pandemic.Anxiety https://ijps.tums.ac.ir/index.php/ijps/article/view/2287 https://ijps.tums.ac.ir/index.php/ijps/article/download/2287/1032

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 110 117 Samin Davoody Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Stella Goeschl Medical University of Vienna, Vienna, Austria. Mahsa Dolatshahi Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran AND Neuroimaging Network (NIN), Universal Scientific Education and Research Network (USERN), Tehran, Iran. Rozita Davari-Ashtiani Department of Psychiatry, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Reyhaneh Saffarpour Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Fatemeh Sodeifian Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Serge Brand 1. Substance Abuse Prevention Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. AND Center for Affective, Stress and Sleep Disorders (ZASS), University of Basel, 4002 Basel, Switzerland AND Sleep Disorders Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran AND Department of Sport, Exercise, and Health, University of Basel, 4002 Basel, Switzerland AND School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. 2021 02 09 Objective: To cope with the COVID-19 pandemic, national health authorities temporarily closed cultural, religious, and educational institutions such as universities and schools. Children and adolescents with ADHD were challenged with the restrictions caused by the Covid-19 pandemic such as homeschooling and reduced physical activity. The present narrative review aimed to summarize the state-of-the-art regarding associations between COVID-19-related social restrictions and possible psychological and behavioral issues in children and adolescents with ADHD. Additionally, we discussed the underlying possible reasons of the association focusing on the role of parental influence and physical activity, vulnerabilities of individuals with ADHD to Covid-19 infection and to school closure and remote learning. Method: To collect data for the present narrative review, recent publications on these topics between February 1st, 2020 and January 10th, 2021 were retrieved from the most popular search engines (PubMed; Scopus; Google Scholar; Psych Info; Embase) through a comprehensive search using relevant keywords. Results: During confinement, children and adolescents with ADHD reported increased behavioral and ADHD-related symptoms and overall decreased psychological well-being. Factors negatively impacting children’s and adolescents’ behavioral symptoms and well-being were: less physical activity, adverse parental behavior, difficulties in coping with preventive guidelines, and school closure and remote learning consequences. Conclusion: Children and adolescents with ADHD and their caregivers faced both specific and general psychological issues related to the school lockdowns and homeschooling. Additionally, Individuals with ADHD seem to be more vulnerable to Covid-19 infection which highlights the need for better healthcare adaptation. https://ijps.tums.ac.ir/index.php/ijps/article/view/2595 https://ijps.tums.ac.ir/index.php/ijps/article/download/2595/1039

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 1 13 Fahimeh Mohseni Center for Health Related Social and Behavioral Sciences Research, Shahroud University of Medical Sciences, Shahroud, Iran. Kasra Rahimi Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran. Mohammad Niroumand Sarvandani Neurosciences Research Center, Shahroud University of Medical Sciences, Shahroud, Iran. Zhaleh Jamali Addiction Research Center, Shahroud University of Medical Sciences, Shahroud, Iran. Seyedeh Masoumeh Seyedhosseini Tamijan Psychiatry and Behavioral Sciences Research Center, Addiction Research Institute, Mazandaran University of Medical Sciences, Sari, Iran. Raheleh Rafaiee Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran. 2020 06 04 Objective: The present study aimed to compare lapse and relapse-free survival between patients treated in Narcotics Anonymous (NA) groups and Methadone Maintenance Treatment (MMT) centers and to determine the relationship between social support scale and treatment outcome. Method: This study was a prospective, 12-month cohort study using the random sampling method to select 100 newcomer patients treated by the NA Association as well as 100 patients in MMT centers. The data were collected using a demographic questionnaire and Social Support Appraisals (SSA) scale at the onset of the study along with follow-up phone calls every other week. Results: All participants were male, aged between 18 and 65 with a mean (SD) age of 38.98 (± 10.85) years. Prevalence of relapse in 12 months was 60.5%. The lapses in the MMT group and relapses in the NA group were significantly higher (P < 0.001). The younger patients with lower levels of education are at greater risk of lapse/relapse. The mean score of SSA was significantly higher in the MMT group than the NA group in all subscales, including friends, family, and the others' support (P < 0.001). The mean scores of SSA subscales for the participants without relapse in the NA group was significantly higher in comparison to the MMT group. Conclusion: Detection of factors related to drug abuse relapse/lapse may help addiction therapists to identify drug abuse patients with lapse/relapse and to develop treatment and policy guidelines to prevent relapse in addiction recovery. https://ijps.tums.ac.ir/index.php/ijps/article/view/2208 https://ijps.tums.ac.ir/index.php/ijps/article/download/2208/1030

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 14 23 Atefeh Zandifar Imam Ali Hospital, Alborz University of Medical Sciences, Karaj, Iran. Rahim Badrfam Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. Hossein Sanjari Moghaddam Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. Shahin Akhondzadeh Psychiatry and Psychology Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. 2021 09 20 Objective: Spironolactone (C24H32O4S), a potent mineralocorticoid receptor (MR) inhibitor, is a potassium-sparing diuretic that is traditionally used to treat fluid build-up in the body or for its anti-androgenic properties. This study is a double-blind, placebo-controlled, randomized clinical trial assessing the beneficial effects of spironolactone in addition to risperidone in improving negative symptoms of schizophrenia. Method: 40 patients with chronic schizophrenia, aged 18–60 years, were assigned to two groups: risperidone + spironolactone or risperidone + placebo. Risperidone was administered to both the spironolactone and placebo groups with a dose up to 6 mg/day throughout the trial. Spironolactone (C24H32O4S) was ordered 100 mg/day for the full 8-week course of the study. Patients were rated on the Positive and Negative Syndrome Scale (PANSS) at four time points: baseline, weeks two, four, and eight. The PANSS negative subscale score was the main objective. Results: PANSS negative, positive, and total scores showed significantly greater improvements in the spironolactone relative to the placebo group from baseline to the trial endpoint (P (Cohen’s d): 0.004 (0.96), 0.007 (0.90), and 0.042 (0.66), respectively). Similarly, ANOVA also presented significant time × treatment interaction effect for spironolactone on PANSS negative (F = 9.04; ηp2 = 0.19; df = 1.38; P = 0.002), positive (F = 3.43; ηp2 = 0.08; df = 2.72; P = 0.023), and total (F = 3.94; ηp2 = 0.09; df = 2.05; P = 0.022) scores. However, spironolactone did not cause significant decrease in the general psychiatric pathology score of PANSS. Conclusion: Our findings suggest the efficacy and safety of spironolactone as an adjunctive therapy to risperidone in improving the symptoms of schizophrenia. https://ijps.tums.ac.ir/index.php/ijps/article/view/2935 https://ijps.tums.ac.ir/index.php/ijps/article/download/2935/1031

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 35 43 Samaneh Mirzaei Dahka Social Determinants of Health Research Center, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran. Saman Maroufizadeh Department of Biostatistics, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran. Moluk Pouralizadeh Department of Nursing, School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran. Tahereh Zahedsefat Head of Nursing, Guilan University of Medical Sciences, Rasht, Iran. Mehrdad Ghanbarpoor Ganjari Department of Psychology, Faculty of Psychology and Educational Sciences, University of Sistan and Baluchestan, Zahedan, Iran. Elaheh Parsasalkisari School of Pharmacy, Debrecen Medical University, Debrecen, Hungary. Atefeh Ghanbari Social Determinants of Health Research Center (SDHRC), School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, Iran. 2020 08 22 Objective: Nurses exposed to COVID-19 could be psychologically stressed. The present study investigated the mental health and the resilience level in the nurses’ population. Method: This cross-sectional study was performed on 432 nurses in 27 hospitals working in Guilan province, north of Iran, between April 29, to May 14, 2020. Mental health and resilience were measured using the 12-item General Health Questionnaire-12 (GHQ-12) and the 10-item Connor-Davidson Resilience Scale (CD-RISC-10). Hierarchical multiple linear regression model was used to identify factors associated with mental health. Results: The mean GHQ-12 and CD-RISC-10 scores were 15.72 (SD, 5.67) and 25.97 (SD, 6.88), respectively. Probable psychological distress (GHQ-12 score ≥ 15) was present in 57.2% of nurses. Among demographic and COVID-19-related variables, only educational level was significantly and negatively correlated with mental health. After controlling the variables, hierarchical regression analyses results showed that lower resilience was associated with poor mental health (β = -0.49; P < 0.001). Conclusion: Regarding the nurses’ mental health, appropriate psychological/psychiatric intervention is necessary, and resilience can play a role as a mental health promoter. https://ijps.tums.ac.ir/index.php/ijps/article/view/2323 https://ijps.tums.ac.ir/index.php/ijps/article/download/2323/1033

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 52 60 Akram Ghorbali Department of Psychology, South Tehran Branch, Islamic Azad University, Tehran, Iran. Mohammad Reza Shaeiri Department of Psychology, Faculty of Humanities, Shahed University, Tehran, Iran. Mohammad Gholami Fesharaki Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. 2020 03 31 Objective: Previous research has shown a relationship between schizotypal personality traits and dissociative tendencies. The Inference-Based Approach (IBA) can explain this relationship to some extent. Purpose of this study was to investigate the mediating role of inferential confusion in relation to dissociative experiences and schizotypal personality traits. Method: A total of 341 students from Shahed University participated in this cross-sectional study. Sampling was conducted randomly by the cluster sampling method. Data were collected using the Inferential Confusion Questionnaire (ICQ-EV), Schizotypal Personality Questionnaire-Brief (SPQ-B), and Dissociative Experiences Scale (DES-II). Data were analyzed using SPSS-22 software based on statistical methods including Pearson correlation, Baron and Kenny hierarchical regression and the Sobel test. Results: There were significant positive relationships between dissociative experiences, schizotypal personality traits, and inferential confusion (P < 0.01). Findings showed that inferential confusion mediates the relationship between dissociative experiences and schizotypal personality traits (β = 0.29; P < 0.001). Conclusion: According to the obtained results, the present study, considering role of inferential confusion, succeeded in explaining the relationship between dissociative experiences and schizotypal personality traits to some extent. https://ijps.tums.ac.ir/index.php/ijps/article/view/2089 https://ijps.tums.ac.ir/index.php/ijps/article/download/2089/1035

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 61 71 Ghazal Davodi-Boroujerd Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Imaneh Abasi Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Abbas Masjedi Arani Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Maryam Aslzaker Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2020 05 27 Objective: Although many studies have investigated the effect of maternal personality on internalizing and externalizing behaviors of a child, the role of both mother and child’s emotional mechanisms in these behaviors is little explored. The present study was focused on the relationship between the mother’s personality, and internalizing and externalizing behaviors of children with the mediating role of children’s alexithymia, mother’s alexithymia, and children’s emotion regulation (ER). Method: 162 mothers and elementary school-aged children were recruited regarding their demographics and completed the NEO personality inventory, Child behavior checklist, Toronto alexithymia scale, Children’s alexithymia measure, and Children’s emotion regulation checklist. Data were analyzed using SPSS (ver.23), and AMOS (ver.23). Results: Structural equations modeling demonstrated an acceptable model fit to data (CMIN/DF = 1.233, RSME = 0.038, GFI = 0.962). Mother’s alexithymia predicted internalizing problems whereas it didn’t predict externalizing problems in children. Also, the bootstrap results indicated that the mother and children’s alexithymia and children’s ER had mediating roles between mother’s personality and externalizing and internalizing problems. Conclusion: The present results demonstrated that mother’s personality can indirectly, through mother and children’s alexithymia and children’s ER act as an important factor in development of mental problems. In other words, findings indicated that children’s emotional development is not a one-way road, but it is a mutual process that involves both the mother and the child. https://ijps.tums.ac.ir/index.php/ijps/article/view/2190 https://ijps.tums.ac.ir/index.php/ijps/article/download/2190/1036

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 72 83 Fatemeh Forouzeh Yekta Department of Psychology, Faculty of Humanities, Shahed University, Tehran, Iran. Hamid Yaghoubi Department of Psychology, Faculty of Humanities, Shahed University, Tehran, Iran. Soheila Ghomian Department of Psychology, Faculty of Humanities, Shahed University, Tehran, Iran. Mohammad Gholami Fesharaki Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran. 2020 11 18 Objective: The present study evaluated the model of mediating variables concerning effectiveness of mindfulness in improving women's marital satisfaction. Method: This study was quasi-experimental with pre-test, post-test and control groups. The statistical population included every married woman in Tehran in the year 1396 (2017). The research sample was composed of 60 married women with moderate marital satisfaction. They were chosen using the convenient sampling technique and were randomly assigned to control and experimental groups. The experimental group attended 8 sessions of Mindfulness-Based Stress Reduction (MBSR) and the control group was on a waiting list. Both groups answered the Five Facet Mindfulness Questionnaire (FFMQ), the Depression, Anxiety, and Stress Scale (DASS), Difficulties in Emotion Regulation Scale (DERS), Interpersonal Reactivity Inventory (IRI), Needs for Intimacy Questionnaire of Bagarozi, Positive and Negative Affect Scale (PANAS) and the Couple Satisfaction Index (CSI) before and at end of intervention. The data were analyzed by Structural Equation Modeling (SEM) using PLS-22 and SPSS-23. Results: In the initial hypothetical model, which included the direct effect of mindfulness on marital satisfaction and its indirect effects through psychological distress, emotion regulation, empathy, marital intimacy and positive emotion on marital satisfaction, coefficients of all model paths were significant at 95% level except direct path of mindfulness to marital satisfaction (t = 1.14), marital intimacy to marital satisfaction (t = 0.48) and positive affection to marital satisfaction (t = 1.75). After removing the non-significant paths, the model was tested again and the model fit index (GOF = 0.47) was a very good fit for the modified overall model. Conclusion: The results identified mindfulness-based stress reduction intervention was effective in enhancing marital satisfaction through reducing psychological distress and improving emotion regulation and empathy. https://ijps.tums.ac.ir/index.php/ijps/article/view/2453 https://ijps.tums.ac.ir/index.php/ijps/article/download/2453/1037

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 84 90 Salman Khazaei Research Center for Health Sciences, Hamadan University of Medical Sciences, Hamadan, Iran. Erfan Ayubi Social Determinants of Health Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Mahdi Khazaei Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran. Mojtaba Khazaei Department of Neurology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. Gita Afrookhteh Department of Psychiatry, Hamadan University of Medical Sciences, Hamadan, Iran. 2020 04 10 Objective: Effective rehabilitation and better quality of life among stroke patients are functions of several factors such as quality and pattern of sleep. The present study aimed to evaluate sleep quality and related determinants in such patients. Method: The present cross-sectional study was performed from October to December 2019 among stroke patients who were admitted to Sina Hospital, Hamadan, Iran. We used the Pittsburgh Sleep Quality Index (PSQI) questionnaire to determine sleep quality in these patients. Significant determinants of the global score of PSQI were identified via multivariable linear regression. Results: A total of 97 stroke patients (age 67±79 years, 55.7% male) were enrolled into the study. Prevalence of poor sleep was 0.84 (95% CI: 0.75, 0.91) in stroke patients. Patients with nervous tension and those with surgical treatment and with Non-hemorrhagic CT scan had a predicted increase of 1.65, 2.91 and 3.25 in the mean of the global PSQI score (P ≤ 0.05), respectively. Conclusion: Nervous tension, treatment method, results of CT scan and cardiac problems may be associated with post-stroke sleep disorder. https://ijps.tums.ac.ir/index.php/ijps/article/view/2107 https://ijps.tums.ac.ir/index.php/ijps/article/download/2107/1043

Tehran University of Medical Sciences Iranian Journal of Psychiatry 1735-4587 17 1 2022 01 01 91 98 EN Javad Sheikhi Koohsar Department of Medical Imaging, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Fariborz Faeghi Department of Medical Imaging, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Raheleh Rafaiee Department of Neuroscience, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran. Mohammad Niroumand Sarvandani Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran. Sadegh Masjoodi Institute for Cognitive and Brain Sciences, Shahid Beheshti University, Tehran, Iran. Hamid Kalalian Moghaddam Department of Physiology, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran. 2020 12 05 Objective: Chronic METH use results in neurodegenerative alternations in the human brain. The present study aimed to assess the long-term METH impact on brain metabolite concentrations in cases meeting the DSM-5 criteria regarding METH use. Method: We recruited 42 METH users meeting the DSM-5 criteria and 21 healthy controls. Psychotic signs were measured using the Positive and Negative Syndrome Scale (PANSS). Proton magnetic resonance spectroscopy (1HMRS) evaluating Myo-inositol (Ml), Choline (Cho), Glutamine plus Glutamate (Glx), N-acetyl aspartate (NAA), and Creatine (Cre) were obtained in the dopaminergic pathway (Frontal Cortex, Substantia nigra, Ventral Tegmental Area (VTA), Nucleus Accumbens (NAc), Hippocampus, Striatum,) the subjects. All participants collected urine specimens for 24 hours to measure presence of specific metabolites including METH metabolite level, 5-Hydroxy indoleacetic acid metabolite (for serotonin level monitoring), and metanephrine metabolite (for dopamine level monitoring). Results: Dopamine and Serotonin increased in the METH group (P < 0.001). METH caused an increase in the Cre (P < 0.001) and a decline in the Glx (P < 0.001), NAA (P = 0.008), and MI (P < 0.001) metabolite concentrations of dopamine circuits in METH users in comparison with healthy subjects. We found no change in Cho metabolite concentration. Psychological data and the neurometabolite concentrations in the studied area of the brain were significantly correlated. Conclusion: There is an association between METH use and active neurodegeneration in the dopamine circuit, and it causes serious mental illness. 1HMRS can detect patient’s deterioration and progression of disease as well as follow-up management in patients with METH use disorder. https://ijps.tums.ac.ir/index.php/ijps/article/view/2475 https://ijps.tums.ac.ir/index.php/ijps/article/download/2475/1042