Comparing Neurocognitive Profile of Patients with Borderline Personality and Bipolar-II Disorders

  • Valiolah Akbari Department of Psychiatry, Qom University of Medical Sciences, Qom, Iran.
  • Parvin Rahmatinejad Mail Clinical Psychology, Forghani Hospital Research Development Committee, Qom University of Medical Sciences, Qom, Iran.
  • Seyed Davood Mohammadi Clinical Psychology, Department of Psychiatry, Medicine School, Fasa University of Medical Sciences, Fasa, Iran
Bipolar Disorder, Borderline Personality Disorder, Neurocognitive Profile


Objective: The present study was conducted to compare neurocognitive profile in patients with borderline personality disorder (BPD) and bipolar II disorder (BD-II) and to find whether BPD can be classified as one of bipolar spectrum disorders.

Method: A total of 35 patients with BPD and 35 euthymic patients with BDII disorder were selected by convenience sampling method. These 2 groups were compared with 30 healthy individuals using neurocognitive battery tests that assessed cognitive flexibility and set-shifting, response inhibition, problem-solving, decision-making, and sustained and selective attention. Data were analyzed using independent t test, X2 and ANOVA.

Results: Patients with euthymic BDII and BPD had poorer performance than the healthy group in most neurocognitive domains (p<0.05). Both patient groups showed similar functions in cognitive flexibility and set-shifting, decision-making, sustained and selective attention, and problem-solving (p<0.05). BPD patients had more elevated response inhibition deficits than BD-II patients (P<0.05). Also, BPD patients had poorer performance in planning compared to BD-II patients (P<0.05).

Conclusion: The results provided empirical support for previous findings which have reported that patients with BPD and BD-II show neurocognitive dysfunctions. Despite the similarity between these 2 clinical groups in terms of neurocognitive profile in this study, more extensive studies are needed to confirm the hypothesis that BPD can be conceptualized as one of bipolar spectrum disorders.


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How to Cite
Akbari V, Rahmatinejad P, Mohammadi SD. Comparing Neurocognitive Profile of Patients with Borderline Personality and Bipolar-II Disorders. Iran J Psychiatry. 14(2):113-119.
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