Continuous Performance Test in Iranian Patients Undergoing Hemodialysis
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Abstract
Objective: Memory and concentration may be affected by hemodialysis in end-stage renal disease. In this study, changes in cognitive function parameters such as attention, impulsiveness, and reaction time were measured and evaluated in the Iranian hemodialysing patients.Methods: In this analytic observational study, cognitive function of 38 hemodialysis patients was measured before and after hemodialysis sessions using Conners' continuous performance test.
Results: Mean age of patients was 37.97 12.58 years. There wasn't any significant difference between numbers of matches successfully recognized, number of Miss Faire and mean of reaction time of those matches successfully recognized before and after hemodialysis. There weren't any differences between history of hemodialysis and number of matches successfully, matches missed and mean reaction time of matches. Educational level of patients was significant effect on number of Miss Faire during hemodialysis.
Conclusions: It has been concluded that hemodialysis did not have any significant impact on the cognitive function. However, this hypothesis needs to be checked and confirmed by careful selection of patients and other cognitive function tests.
Murray AM, Tupper DE, Knopman DS, Gilbertson DT, Pederson SL, Li S, et al. Cognitive impairment in hemodialysis patients is common. Neurology 2006; 67: 216-223.
Brickman AL, Yount SE, Blaney NT, Rothberg S, De-Nour AK. Pathogenesis of cognitive complaints in patients on hemodialysis. Gen Hosp Psychiatry 1996; 18: 36-43.
Harum P, Galvez O, Mayol LG, Blanchard R. Immediate and delayed memory recall patterns of chronic hemodialysis adult hispanic patients. J Ren Nutr 2003; 13: 98-104.
Evans JD, Wagner CD, Welch JL. Cognitive status in hemodialysis as a function of fluid adherence. Ren Fail 2004; 26: 575-581.
Borgaro S, Pogge DL, DeLuca VA, Bilginer L, Stokes J, Harvey PD. Convergence of different versions of the continuous performance test: clinical and scientific implications. J Clin ExpNeuropsychol 2003; 25: 283-292.
Advokat C, Martino L, Hill BD, Gouvier W. Continuous Performance Test (CPT) of college students with ADHD, psychiatric disorders, cognitive deficits, or no diagnosis. J Atten Disord 2007; 10: 253-256.
Avila MT, Robles O, Hong LE, Blaxton TA, Myers CS, Wonodi I, et al. Deficits on the Continuous Performance Test within the schizophrenia spectrum and the mediating effects of family history of schizophrenia. J Abnorm Psychol 2006; 115: 771-778.
Borgatti R, Piccinelli P, Montirosso R, Donati G, Rampani A, Molteni L, et al. Study of attentional processes in children with idiopathic epilepsy by Conners' Continuous Performance Test. J Child Neurol 2004; 19: 509-515.
Fazekas G, Fazekas F, Schmidt R, Kapeller P, Offenbacher H, Krejs GJ. Brain MRI findings and cognitive impairment in patients undergoing chronic hemodialysis treatment. J Neurol Sci 1995; 134: 83-88.
Altmann P, Barnett ME, Finn WF. Cognitive function in Stage 5 chronic kidney disease patients on hemodialysis: no adverse effects of lanthanum carbonate compared with standard phosphate- binder therapy. Kidney Int 2007; s71: 252-259.
Vasil'eva IA, Petrova NN. [Characteristics of the intellectual-memory function of patients treated by chronic hemodialysis]. Klin Med (Mosk) 1991; 69: 80-82.
Ratner DP, Adams KM, Levin NW, Rourke BP. Effects of hemodialysis on the cognitive and sensory-motor functioning of the adult chronic hemodialysis patient. J Behav Med 1983; 6: 291- 311.
Smith BC, Winslow EH. Cognitive changes in chronic renal patients during hemodialysis. Anna J 1990; 17: 283-286; discussion 287.
Singh NP, Sahni V, Wadhwa A, Garg S, Bajaj SK, Kohli R, et al. Effect of improvement in anemia on electroneurophysiological markers (P300) of cognitive dysfunction in chronic kidney disease. Hemodial Int 2006; 10: 267-273.
Kurella M, Mapes DL, Port FK, Chertow GM. Correlates and outcomes of dementia among dialysis patients: the Dialysis Outcomes and Practice Patterns Study. Nephrol Dial Transplant 2006; 21: 2543-2548.
Vos PF, Zilch O, Jennekens-Schinkel A, Salden M, Nuyen J, Kooistra MM, et al. Effect of short daily home haemodialysis on quality of life, cognitive functioning and the electroencephalogram. Nephrol Dial Transplant 2006; 21: 2529-2535.
Tyrrell J, Paturel L, Cadec B, Capezzali E, Poussin G. Older patients undergoing dialysis treatment: cognitive functioning, depressive mood and health- related quality of life. Aging Ment Health 2005; 9: 374-379.
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| Issue | Vol 1 No 4 (2006) | |
| Section | Articles | |
| Keywords | ||
| Memory Hemodialysis Cognitive function | ||
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