Quantitative electroencephalogram (QEEG) Spectrum Analysis of Patients with Schizoaffective Disorder Compared to Normal Subjects.

  • Mahdi Moeini University of Social Welfare and Rehabilitation Sciences, Razi Psychiatric Hospital, Tehran, Iran
  • Ali Khaleghi Psychiatry & Psychology Research Center, Tehran University of Medical Sciences, Tehran, Iran ; Department of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, Iran
  • Nasrin Amiri University of Social Welfare and Rehabilitation Sciences, Razi Psychiatric Hospital, Tehran, Iran
  • Zahra Niknam University of Social Welfare and Rehabilitation Sciences, Razi Psychiatric Hospital, Tehran, Iran
Keywords:
Power spectra, Predominant wave, Quantitative electroencephalogram (QEEG), Relative power, schizoaffective

Abstract

Objective: The aim of this study was to achieve a better understanding of schizoaffective disorder. Therefore, we obtained electroencephalogram (EEG) signals from patients with schizoaffective disorder and analyzed them in comparison to normal subjects.
Method: Forty patients with schizoaffective disorder and 40 normal subjects were selected randomly and their electroencephalogram signals were recorded based on 10-20 international system by 23 electrodes in open- and closed-eyes while they were sitting on a chair comfortably. After pre-processing for noise removal and artifact reduction, we took 60- second segments from each recorded signals. Then, the absolute and relative powers of these segments were evaluated in all channels and in 4 frequency bands (i.e., delta, theta, alpha and beta waves). Finally, Data were analyzed by independent t-test using SPSS software.
Results:
A significant decrease in relative power in the alpha band, a significant decrease in power spectra in the alpha band and a significant increase in power spectra in the beta band were found in patients compared to normal subjects (P < 0.05). The predominant wave in the centro-parietal region was the beta wave in patients, but it was the alpha band in normal subjects (P = 0.048). Also, the predominant wave of the occipital region in patients was the delta wave, while it was the alpha wave in normal subjects (P = 0.038).
Conclusion: Considering the findings, particularly based on the significant decrease of the alpha waves in schizoaffective patients, it can be concluded that schizoaffective disorder can be seen in schizophrenia spectrum.

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How to Cite
1.
Moeini M, Khaleghi A, Amiri N, Niknam Z. Quantitative electroencephalogram (QEEG) Spectrum Analysis of Patients with Schizoaffective Disorder Compared to Normal Subjects. Iran J Psychiatry. 9(4):216-221.
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