Evaluation of Sleep Problems in Preeclamptic, Healthy Pregnant and Non-Pregnant Women
Abstract
Objective: Sleep problems are common complaints among pregnant women. This study was designed to compare subjective sleep problems in non-pregnancy condition, healthy and preeclamptic pregnancy as a major complication of pregnancy. We hypothesized that some sleep problems are more prevalent in females with preeclampsia.
Methods: In this cross-sectional study, 102 women with preeclampsia, 106 healthy pregnant women in the third trimester and 103 healthy non-pregnant women were selected through random sampling. Age and parity were matched in the three groups. We used Global sleep assessment questionnaire (GSAQ) to check the subjective sleep
problems, and then we performed statistical analysis using Analysis of variance (ANOVA) and Pearson Chi-square tests.
Results: Our findings revealed significant differences in initial insomnia (p = 0.034), fragmented sleep (p = 0.022), snoring (p<0.001), non-idiopathic insomnia (p = 0.045) and sadness and anxiety (p = 0.001) between the three groups. Some sleep problems were more common in preeclampctic compared to healthy pregnant women including initial insomnia, fragmented sleep, snoring, sleep apnea and non-idiopathic insomnia. Moreover, the subjects with preeclampsia revealed more fragmented sleep, snoring, sadness and anxiety and lack of getting enough sleep due to other activities compared to nonpregnant women.
Conclusion: Different kinds of sleep problems can occur in subjects with preeclampsia in comparison with the non-pregnant and healthy pregnant subjects. Sleep problems should be evaluated during pregnancy, particularly in pregnant women with preeclampsia, and suitable treatment should be provided for any specific sleep problem.
Pien GW, Schwab RJ. Sleep disorders during pregnancy. Sleep 2004; 27: 1405-1417.
Ward BA. Insomnia during pregnancy. Current Clinical Neurology. 2010; 2:103-115.
Lee KA, Caughey AB. Evaluating insomnia during pregnancy and postpartum. Current Clinical Neurology, 2006;4: 185-198.
Broughton PF. The hypertensive disorders of pregnancy. BMJ 1995; 311: 609-613.
Perloff D. Hypertension and pregnancy related hypertension. Cardiol Clin 1998; 16: 79-101
Granger JP, Alexander BT, Llinas MT, Bennett WA, Khalil RA. Pathophysiology of Preeclampsia: Linking Placental Ischemia/Hypoxia with Microvascular Dysfunction. Microcirculation 2002; 9: 147-160.
Yinon D, Lowenstein L, Suraya S, Beloosesky R, Zmora O, Malhotra A, et al. Pre-Eclampsia Is Associated with Sleep-Disordered Breathing and Endothelial Dysfunction. Eur Respir J 2006; 27: 328-333.
Okun ML, Roberts JM, Marsland AL, Hall M. How disturbed sleep may be a risk factor for adverse pregnancy outcomes a hypothesis. Obstet Gynecol Surv 2009; 64: 273-280.
Roth T, Zammit G, Kushida C, Doghramji K, Mathias SD, Wong JM, Buysse DJ. A new questionnaire to detect sleep disorders. Sleep Med. 2002; 3: 99-108.
Razazian N, Rezaei M. Sleep disorders. Professional Med J Aug 2012; 19: 508-512.
Bjorvatan B, Sagen IM, Oyane N. The association between sleep duration, body mass index and metabolic measures in the Hordaland Health Study. J Sleep Res 2007;16: 66-76.
Suarez EC. Self-reported symptoms of sleep disturbance and inflammation, coagulation, insulin resistance and psychological distress: evidence for gender disparity. Brain Behav Immun 2008; 22: 960-968.
Vgontzas AN, Lin HM, Papaliaga M. Short sleep duration and obecity: the role of emotional stress and sleep disturbance. Int J Obes 2008; 32: 801-809.
Franklin KA, Holmgren PA, Jonsson F, Poromaa N, Stenlund H, Svanborg E. Snoring, pregnancy-induced hypertension, and growth retardation of the fetus.Chest 2000; 117: 137-141.
Edwards N, Blyton DM, Kirjavainen T, Kesby GJ, Sullivan CE. Nasal continuous positive airway pressure reduces sleep-induced blood pressure increments in pre-eclampsia. Am J Respir Crit Care Med 2000; 162: 252-257.
Edwards N, Blyton DM, Kesby GJ, Wilcox I, Sullivan CE. Pre-eclampsia is associated with marked alternations in sleep architecture. Sleep 2000; 23: 619-625.
Champagne K, Schwartzman K, Opatrny L, Barriga P, Morin L, Mallozzi A, et al. Obstructive Sleep Apnoea and Its Association with Gestational Hypertension. Eur Respir J 2009; 33: 559-565.
Edwards N, Blyton CM, Kesby GJ, Wilcox I, Sullivan CE. Pre-eclampsia is associated with marked alterations in sleep architecture. Sleep 2000; 23: 619-625.
Khazaie H, Najafi F, Rezaie L, Tahmasian M, Sepehry AA, Herth FJ. Prevalence of symptoms and risk of obstructive sleep apnea syndrome in the general population. Arch Iran Med 2011; 14: 335-8.
Goyal D, Gay C, Lee K. Fragmented maternal sleep is more strongly correlated with depressive symptoms than infant temperament at three months postpartum.Arch Womens Ment Health 2009; 12: 229-237.
Khazaie H, Ghadami MR, Knight DC, Emamian F and Tahmasian M. Insomnia Treatment in the Third Trimester of Pregnancy Reduces Postpartum Depression Symptoms: A Randomized Clinical Trial. Psychiatry Res 2013; 210: 901-905.
Tahmasian M, Khazaie H, Sepehry AA, Russo MB. Ambulatory monitoring of sleep disorders. J Pak Med Assoc 2010; 60: 480-487.
Tahmasian M, Khazaie H, Golshani S, Avis KT. Clinical application of actigraphy in psychotic disorders: A systematic review. Curr Psychiatry Rep 2013; 15: 359.
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Issue | Vol 8 No 4 (2013) | |
Section | Articles | |
Keywords | ||
Global sleep assessment questionnaire (GSAQ) Preeclampsia pregnancy sleep problems |
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